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DGKα-IN-10

DGKα Inhibitor

DGKα-IN-10 is a potent inhibitor of diacylglycerol kinase alpha (DGKα), exhibiting an IC50 of 0.27 nM. This compound has been shown to enhance IL-2 release and promote T cell proliferation, making it valuable for immunological studies. DGKα-IN-10 is suitable for research applications focused on cancer immunotherapy, particularly in the context of colon cancer.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2980579-79-9
Applications	DGKα Inhibitor
Formula	C₂₅H₂₅N₅O₄
Molecular Weight	459.50
SMILES	N#CC1=NC2=C(N(C)C(C=C2N3CCC(C4=NC5=CC(C)=CC=C5O4)CC3)=O)C=C1OCCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.