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DGKα-IN-4

DGKα Inhibitor

DGKα-IN-4 is a selective diacylglycerol kinase alpha (DGKα) inhibitor with an IC50 of 0.1 nM. This compound enhances the anti-tumor efficacy of anti-PD-1 therapies by promoting T cell proliferation and function. DGKα-IN-4 is poised to advance research in the fields of oncology and immunology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2648723-43-5
Applications	DGKα Inhibitor
Formula	C₃₀H₂₉N₅O₄
Molecular Weight	523.58
SMILES	N#CC1=CC2=C(N(C)C(C(C#N)=C2N3CCC(C)(CC3)C4=NC5=C(O4)C=CC(C)=C5)=O)C=C1OC6COCC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.