Fig. 1 · Structure

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DGKα-IN-6

DGKα Inhibitor

DGKα-IN-6 is a selective inhibitor of diacylglycerol kinase alpha (DGKα), exhibiting an IC50 of 1.377 nM. This compound has demonstrated potential for use in cancer research, providing insights into the role of DGKα in tumor biology and signaling pathways. Researchers can utilize DGKα-IN-6 to explore its effects on cell proliferation and survival in various cancer models.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2886734-91-2
Applications DGKα Inhibitor
Formula C25H21F3N6
Molecular Weight 462.47
SMILES
FC(F)(C1=NC2=C(C(N3C4=C(CCC3)C(C#CC5(CC5)C)=CC=C4)=NC6=NN=C(C)N62)C=C1)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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