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DGKα-IN-8

DGKα Inhibitor

DGKα-IN-8 is a selective diacylglycerol kinase alpha (DGKα) inhibitor, exhibiting an IC50 value of 22.491 nM and an EC50 of 0.256 nM. This compound is valuable for research in oncology, particularly in the study of solid tumors, as well as in virology, including investigations into HIV and hepatitis B virus infections. DGKα-IN-8 provides a tool for elucidating the role of DGKα in various cellular processes and disease mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2886717-70-8
Applications	DGKα Inhibitor
Formula	C₂₃H₁₉ClF₃N₅O
Molecular Weight	473.88
SMILES	FC1=CC(N(CC(F)F)C2=NC3=C(C4=C2C=CC(Cl)=C4)N(C)N=N3)=CC(C#CC(C)(C)O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.