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DGKζ-IN-6

DGKζ Inhibitor

DGKζ-IN-6 is a selective inhibitor of diacylglycerol kinase zeta (DGKζ) with an IC50 of 45.5 nM. This compound effectively inhibits the secretion of interleukin-2 (IL-2), making it relevant for research into cancer and autoimmune diseases. Its ability to modulate IL-2 release positions DGKζ-IN-6 as a valuable tool for investigating the role of DGKζ in immune responses and related therapeutic pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3058005-75-4
Applications	DGKζ Inhibitor
Formula	C₂₂H₂₁FN₄O₃S
Molecular Weight	440.49
SMILES	CC(N(C1=NC(N)=C(S1)C(C2=CC=C(C=C2)OC3CC3)=O)C4=CC=C(C=C4)F)C(N)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.