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DGKζ-IN-7

DGKζ Inhibitor

DGKζ-IN-7 is a potent DGKζ inhibitor with an IC50 value of 33.4 nM. This compound effectively inhibits the secretion of IL-2, making it a valuable tool for investigating mechanisms in cancer and autoimmune disease research. Its oral bioavailability adds convenience for in vivo studies, facilitating deeper exploration of DGKζ's role in immune regulation and tumorigenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3058006-33-7
Applications	DGKζ Inhibitor
Formula	C₁₉H₁₆F₆N₄O₂S₂
Molecular Weight	510.48
SMILES	O=C(C(C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(S(F)(F)(F)(F)F)C=C3)=O)S2)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.