Documents & Downloads

DGN462

DNA-alkylating Agent

DGN462 is a potent DNA-alkylating agent targeting DNA to induce cytotoxicity in cancer cells. It exhibits significant anti-tumor activity, particularly in acute myeloid leukemia (AML). DGN462 is suitable for use as a cytotoxic component in antibody-drug conjugates (ADCs), facilitating targeted therapy in oncological research applications.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	1394079-41-4
Applications	DNA-alkylating Agent
Formula	C₅₃H₅₉N₅O₉S
Molecular Weight	942.13
SMILES	O=C1N2[C@](CC3=C2C=CC=C3)([H])CNC4=CC(OCC5=CC(N(CC(C)(S)C)CCOCCOCCOC)=CC(COC6=C(OC)C=C7C(N8[C@](CC9=C8C=CC=C9)([H])C=NC7=C6)=O)=C5)=C(OC)C=C14

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.