Fig. 1 · Structure
Documents & Downloads
dGTP
Guanosine Nucleotide
dGTP (2'-Deoxyguanosine-5'-triphosphate) functions as a crucial precursor for DNA synthesis and acts as a direct substrate in DNA replication and repair processes. Given its role in the nucleotide pool, dGTP can be particularly vulnerable to oxidative stress, leading to its oxidation and the formation of 8-oxo-dGTP in the presence of reactive oxygen species. This compound is essential for various research applications, including studies on DNA polymerase activity and the mechanisms of DNA damage and repair.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 2564-35-4 |
| Applications | Guanosine Nucleotide |
| Formula | C10H16N5O13P3 |
| Molecular Weight | 507.18 |
| Synonyms | 2'-Deoxyguanosine-5'-triphosphate |
| SMILES | O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.