Fig. 1 · Structure
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DH03
PROTAC Target Protein Ligand
DH03 is a PROTAC target protein ligand that exhibits binding affinity for the SARS-CoV-2 main protease (MPro). This compound plays a crucial role in the development of PROTAC molecules, such as PROTAC SARS-CoV-2 Degrader-1. Its ability to facilitate targeted protein degradation makes DH03 a valuable tool in antiviral drug research and therapeutic development aimed at combating SARS-CoV-2.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 361162-95-0 |
| Applications | PROTAC Target Protein Ligand |
| Formula | C18H14ClFN4O |
| Molecular Weight | 356.78 |
| Synonyms | 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-ethoxyquinoline-3-carbonitrile |
| SMILES | N#CC1=C(NC2=CC(Cl)=C(F)C=C2)C(C(N=C1)=C3)=CC(N)=C3OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.