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DHFS-IN-1

DHFS Inhibitor

DHFS-IN-1 is a potent inhibitor of dihydrofolate synthetase (DHFS) with an IC50 value of 2.6 μM. This compound is utilized in research focused on infectious diseases that involve bacterial folate synthesis, providing valuable insights into potential therapeutic strategies targeting bacterial growth and proliferation. Its specificity for DHFS makes it a useful tool for elucidating the role of folate pathways in pathogenic bacteria.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2995300-60-0
Applications	DHFS Inhibitor
Formula	C₁₆H₁₆N₈O₂
Molecular Weight	352.35
SMILES	NC1=NC(N)=NC2=NC=C(CNC3=CC=C(C4(O)C(NC4)=O)C=C3)N=C12

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.