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DHPS-IN-3

DHPS Inhibitor

DHPS-IN-3 is a NAD-competitive inhibitor of dihydropteroate synthase (DHPS), demonstrating an IC50 of 0.0092 μM in the presence of 14 μM NAD and 0.069 μM with 250 μM NAD. This compound showcases significant potential in cancer research, targeting metabolic pathways crucial for tumor progression. Researchers can utilize DHPS-IN-3 to investigate the role of DHPS inhibition in various cancer models and explore therapeutic strategies that disrupt folate biosynthesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2470012-40-7
Applications	DHPS Inhibitor
Formula	C₁₈H₂₃N₃OS
Molecular Weight	329.46
SMILES	O=C1C2=C(CCN1[C@@H](CN)CC(C)C)C(C3=CN=CC=C3)=CS2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.