Fig. 1 · Structure
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DHX9-IN-10
DHX9 Inhibitor
DHX9-IN-10 is a selective inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 9.04 μM in cellular target engagement studies. This compound is valuable for investigating the role of DHX9 in cancer biology and can be utilized in research settings focused on RNA metabolism and therapeutic development. Its inhibition of DHX9 provides insights into mechanisms of oncogenesis and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2973746-79-9 |
| Applications | DHX9 Inhibitor |
| Formula | C19H18N2O3S2 |
| Molecular Weight | 386.49 |
| SMILES | O=C(C1=CC(C2=CC=CC=C2)=C(C)S1)NC3=CC=CC(NS(=O)(C)=O)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.