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DHX9-IN-11

DHX9 Inhibitor

DHX9-IN-11 is a selective inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 0.0838 μM in cellular assays. This compound is primarily utilized in cancer research, facilitating investigations into the role of DHX9 in tumorigenesis and its potential as a therapeutic target. Its activity provides a valuable tool for elucidating the molecular mechanisms involving RNA processing and regulation in cancer cells.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2973402-91-2
Applications	DHX9 Inhibitor
Formula	C₂₃H₂₃ClF₃N₅O₃S
Molecular Weight	541.97
SMILES	O=C(C1=CN(C)C(C2=C(F)C=C(N3CCC(F)(CC3)F)C=N2)=C1)NC4=CC(Cl)=CC(NS(=O)(C)=O)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.