Fig. 1 · Structure
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DHX9-IN-12
DHX9 Inhibitor
DHX9-IN-12 is an inhibitor targeting the RNA helicase DHX9, exhibiting an EC50 of 0.917 μM for cellular target engagement. This compound is primarily utilized in cancer research to investigate the regulatory roles of DHX9 in tumor biology and RNA metabolism. Its application aids in the understanding of molecular mechanisms underlying various cancer types, facilitating the development of potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2973747-13-4 |
| Applications | DHX9 Inhibitor |
| Formula | C18H17N3O3S2 |
| Molecular Weight | 387.48 |
| SMILES | O=C(C1=CC(C2=NC=CC=C2C)=CS1)NC3=CC=CC(NS(=O)(C)=O)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.