Fig. 1 · Structure
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DHX9-IN-14
DHX9 Inhibitor
DHX9-IN-14 is a specific inhibitor of the RNA helicase DHX9, demonstrating an effective EC50 value of 3.4 μM for cellular target engagement. This compound plays a critical role in cancer research, where modulation of DHX9 activity has potential therapeutic implications. It is valuable for investigating the involvement of DHX9 in various oncogenic processes and biological pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2973747-90-7 |
| Applications | DHX9 Inhibitor |
| Formula | C18H16F2N4O3S |
| Molecular Weight | 406.41 |
| SMILES | CN1C=C(C=C1C2=NC=C(C=C2F)F)C(NC3=CC(NS(C)(=O)=O)=CC=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.