Fig. 1 · Structure

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DHX9-IN-15

DHX9 Inhibitor

DHX9-IN-15 is a selective inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.232 μM in cellular assays. This compound significantly disrupts DHX9 activity, making it a valuable tool for investigating its role in oncology and cancer-related pathways. Its unique mechanism positions it as an important reagent for research into cancer therapeutics and RNA biology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2973398-27-3
Applications DHX9 Inhibitor
Formula C19H19ClN4O4S
Molecular Weight 434.90
SMILES
O=C(C1=CN(C2=NC=CC=C2)C(C(C)O)=C1)NC3=CC(Cl)=CC(NS(=O)(C)=O)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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