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DHX9-IN-16

DHX9 Inhibitor

DHX9-IN-16 is a selective inhibitor of the RNA helicase DHX9, demonstrating an EC50 value of 0.125 μM in cellular target engagement. This compound is employed in cancer research to investigate the role of DHX9 in various neoplastic processes and cellular functions. Its ability to modulate RNA helicase activity makes it a valuable tool for studying mRNA metabolism and potential therapeutic pathways in oncology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2973397-48-5
Applications	DHX9 Inhibitor
Formula	C₁₉H₂₀ClN₅O₄S
Molecular Weight	449.91
SMILES	O=C(C1=CN(C2=NC=C(C=N2)OCC)C(C)=C1)NC3=CC(Cl)=CC(NS(=O)(C)=O)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.