Fig. 1 · Structure

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DHX9-IN-3

DHX9 Inhibitor

DHX9-IN-3 is a potent inhibitor of the ATP-dependent RNA helicase A (DHX9). With an IC50 of 8.7 nM, DHX9-IN-3 effectively inhibits cellular proliferation in LS411N cancer cells. This compound serves as a valuable tool for researchers investigating the role of DHX9 in cancer biology and therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2973401-57-7
Applications DHX9 Inhibitor
Formula C24H20ClFN4O4S2
Molecular Weight 547.02
SMILES
O=C(C1=CC(C2=NC=CC=C2OCC3=CC(F)=CN=C3)=C(C)S1)NC4=CC(Cl)=CC(NS(=O)(C)=O)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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