Fig. 1 · Structure
Documents & Downloads
di-Pal-MTO
siRNA-delivered Nanoparticle
di-Pal-MTO is a lipid designed for siRNA-delivered nanoparticle applications, formed by conjugating the anticancer drug mitoxantrone (MTO) with palmitoleic acid. This compound enhances the efficacy of siRNA delivery into cells, facilitating targeted gene silencing while simultaneously offering enhanced anticancer activity. The combination of di-Pal-MTO with mono-Pal-MTO in a 1:1 molar ratio provides a novel approach to improving therapeutic outcomes in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1349197-90-5 |
| Applications | siRNA-delivered Nanoparticle |
| Formula | C54H84N4O8 |
| Molecular Weight | 917.27 |
| SMILES | CCCCCC/C=C\CCCCCCCC(OCCNCCNC1=C2C(C(C3=C(O)C=CC(O)=C3C2=O)=O)=C(C=C1)NCCNCCOC(CCCCCCC/C=C\CCCCCC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.