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Dichotomine C

Antiallergic Agent

Dichotomine C is a β-carboline-type alkaloid that functions as an antiallergic agent. It effectively inhibits the release of β-hexosaminidase in RBL-2H3 cells, exhibiting an IC50 of 62 μM. Additionally, Dichotomine C suppresses antigen-IgE-mediated release of TNF-α and IL-4 in RBL-2H3 cells with IC50 values of 19 μM and 15 μM, respectively. This compound is suitable for research related to type I allergic reactions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	755036-45-4
Applications	Antiallergic Agent
Formula	C₁₅H₁₄N₂O₄
Molecular Weight	286.28
Synonyms	(R)-(-)-Dichotomine C
SMILES	OC[C@@H](C1=C2C(C3=CC=CC=C3N2)=CC(C(OC)=O)=N1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.