Diclofenac-d4 sodium is a deuterated form of the potent nonselective anti-inflammatory agent Diclofenac sodium, primarily targeting cyclooxygenase (COX) enzymes. It demonstrates effective COX inhibition, with IC50 values of 4 nM for human COX-1 and 1.3 nM for COX-2, along with 5.1 μM and 0.84 μM for ovine COX-1 and COX-2, respectively. This compound also induces apoptosis in neural stem cells through the activation of the caspase cascade, making it valuable for research in inflammation and neurobiology.
Diclofenac-d4 sodium is a deuterated form of the potent nonselective anti-inflammatory agent Diclofenac sodium, primarily targeting cyclooxygenase (COX) enzymes. It demonstrates effective COX inhibition, with IC50 values of 4 nM for human COX-1 and 1.3 nM for COX-2, along with 5.1 μM and 0.84 μM for ovine COX-1 and COX-2, respectively. This compound also induces apoptosis in neural stem cells through the activation of the caspase cascade, making it valuable for research in inflammation and neurobiology.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
