Fig. 1 · Structure
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Dicyclomine
Muscarinic Cholinergic Receptors Antagonist
Dicyclomine is a potent antagonist of muscarinic cholinergic receptors, with a significant affinity for the M1 receptor subtype (Ki=5.1 nM) and the M2 receptor subtype (Ki=54.6 nM) found in brush-border and basal plasma membranes. This compound exhibits antispasmodic properties, effectively alleviating smooth muscle spasms in the gastrointestinal tract. Dicyclomine is primarily utilized in research applications investigating gastrointestinal motility disorders and cholinergic signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 77-19-0 |
| Applications | Muscarinic Cholinergic Receptors Antagonist |
| Formula | C19H35NO2 |
| Molecular Weight | 309.49 |
| Synonyms | Dicycloverine |
| SMILES | O=C(C1(C2CCCCC2)CCCCC1)OCCN(CC)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.