Fig. 1 · Structure
Documents & Downloads
Didesethyl chloroquine
Chloroquine Metabolites
Didesethyl chloroquine, the principal metabolite of chloroquine, primarily targets cardiac mitochondria. It exhibits significant myocardial inhibitory activity, reducing calcium binding and accumulation while inducing mitochondrial swelling and conformational changes. Additionally, didesethyl chloroquine demonstrates inhibitory effects on the growth of Plasmodium falciparum strains. This compound serves as a valuable tool for researching malaria, chikungunya virus infections, and various cardiovascular and cerebrovascular diseases.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 4298-14-0 |
| Applications | Chloroquine Metabolites |
| Formula | C14H18ClN3 |
| Molecular Weight | 263.77 |
| Synonyms | Bisdesethylchloroquine |
| SMILES | CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.