Fig. 1 · Structure
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Diethyl bipy55'DC
CP4Hs Inhibitor
Diethyl bipy55'DC is a selective inhibitor of collagen proline 4-hydroxylases (CP4Hs), demonstrating significant antifibrotic and anti-metastatic properties. This compound effectively inhibits CP4H enzymatic activity in cultured cells at concentrations that do not induce iron deficiency, making it a valuable tool for investigating the roles of CP4Hs in fibrotic diseases and cancer metastasis. Its application extends to studying collagen synthesis and modifying extracellular matrix dynamics in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1762-46-5 |
| Applications | CP4Hs Inhibitor |
| Formula | C16H16N2O4 |
| Molecular Weight | 300.31 |
| SMILES | O=C(C1=CN=C(C2=CC=C(C(OCC)=O)C=N2)C=C1)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.