Fig. 1 · Structure
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Diethyl succinate
Inflammation Protectant
Diethyl succinate, a diester of succinic acid, primarily targets inflammation by acting as a protective agent in biological systems. It penetrates cellular membranes effectively, integrating into tissue cultures where it undergoes metabolism through the tricarboxylic acid cycle. Diethyl succinate has been shown to modulate microglial cell polarization and activation by reducing mitochondrial fission and lowering levels of reactive oxygen species (ROS), thereby providing an inflammatory protective effect in primary microglial cells. Its non-toxic nature makes it suitable for various research applications, including studies on neuroinflammation and metabolic pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 123-25-1 |
| Applications | Inflammation Protectant |
| Formula | C8H14O4 |
| Molecular Weight | 174.19 |
| Synonyms | Diethyl Butanedioate |
| SMILES | O=C(OCC)CCC(OCC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.