Fig. 1 · Structure
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Diethylcarbamazine
Microfilaricidal Agent
Diethylcarbamazine is an orally active microfilaricidal agent primarily used in the treatment of onchocerciasis and lymphatic filariasis. It exhibits biological activities by reducing eosinophil trafficking to lung tissue and showing anti-allergic properties. Additionally, diethylcarbamazine lowers serum levels of various inflammatory markers and ameliorates insulin resistance without significant changes in body weight or organ size. This compound can facilitate research on bronchial asthma, insulin resistance, and related infectious diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 90-89-1 |
| Applications | Microfilaricidal Agent |
| Formula | C10H21N3O |
| Molecular Weight | 199.29 |
| SMILES | O=C(N1CCN(C)CC1)N(CC)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.