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Difluorocyclooctyne-CH2-benzoic acid

DIFO Analogue

Difluorocyclooctyne-CH2-benzoic acid is a difluorinated cyclooctyne (DIFO) analogue that targets azides for efficient click chemistry applications. This reagent enables bioorthogonal labeling and imaging of glycans on live cells, facilitating real-time studies of carbohydrate interactions. Additionally, it includes an alkyne group, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it a versatile tool in chemical biology and bioconjugation research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1047997-30-7
Applications	DIFO Analogue
Formula	C₁₆H₁₆F₂O₂
Molecular Weight	278.29
SMILES	O=C(C1=CC=C(CC2CCCCC#CC2(F)F)C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.