Fig. 1 · Structure
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Difluorocyclooctyne-CH2-COOH
difluorinated Cyclooctyne analog
Difluorocyclooctyne-CH2-COOH is a difluorinated cyclooctyne analog that facilitates strain-promoted alkyne-azide cycloaddition. It exhibits rapid reactivity with azides under physiological conditions, allowing for selective labeling of glycan structures on live cells without the need for copper catalysis. This reagent is particularly valuable in bioorthogonal chemistry for imaging and tracking glycan expressions, enabling in-depth studies of cellular processes and interactions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1047997-31-8 |
| Applications | difluorinated Cyclooctyne analog |
| Formula | C10H12F2O2 |
| Molecular Weight | 202.20 |
| SMILES | O=C(O)CC1C(F)(F)C#CCCCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.