Dihydrexidine hydrochloride (DAR-0100 hydrochloride)

Catalog No.: A59859
D1/D5 Dopamine Receptor Agonist
Dihydrexidine hydrochloride is a potent and selective agonist of the D1-like dopamine receptors (D1/D5), exhibiting an IC50 of 10 nM for the D1 receptor. This compound demonstrates significant antiparkinsonian activity, making it valuable in neurological research. Additionally, Dihydrexidine hydrochloride has been shown to stimulate YAP phosphorylation, indicating its potential role in cellular signaling studies.
Grouped product items
Size Price Stock Qty
1mg
$255.00
In stock
5mg
$575.00
In stock
10mg
$925.00
In stock
25mg
$1,680.00
In stock
50mg
$2,705.00
In stock
100mg
$3,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDihydrexidine hydrochloride is a potent and selective agonist of the D1-like dopamine receptors (D1/D5), exhibiting an IC50 of 10 nM for the D1 receptor. This compound demonstrates significant antiparkinsonian activity, making it valuable in neurological research. Additionally, Dihydrexidine hydrochloride has been shown to stimulate YAP phosphorylation, indicating its potential role in cellular signaling studies.
Product Information
Catalog NumA59859
FormulaC17H18ClNO2
Molecular Weight303.78
CAS Number137417-08-4
SMILESOC1=C(O)C=C(CC[C@]2([H])[C@]3([H])C4=C(C=CC=C4)CN2)C3=C1.Cl
SynonymsDAR-0100 hydrochloride
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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