Fig. 1 · Structure
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Dihydrokainic acid
GLT1 Inhibitor
Dihydrokainic acid is a potent inhibitor of glutamate transporter 1 (GLT1), exhibiting high-affinity binding that effectively disrupts its transport activity. By inhibiting the uptake of glutamate, it increases extracellular glutamate levels, which can modulate neuronal excitability and neurotransmission. This compound is primarily utilized in neuroscience research, particularly in studies focusing on glutamate's role in neural functions, epilepsy, and cognitive processes such as learning and memory.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 52497-36-6 |
| Applications | GLT1 Inhibitor |
| Formula | C10H17NO4 |
| Molecular Weight | 215.25 |
| SMILES | O=C(O)C[C@@H]1[C@@H](C(O)=O)NC[C@@H]1C(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.