Fig. 1 · Structure
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Dihydrouracil
Metabolite of Uracil
Dihydrouracil is a metabolite of uracil and serves as an important marker for identifying dihydropyrimidine dehydrogenase (DPD) deficiency. Its measurement is crucial in pharmacogenomics, particularly in predicting the efficacy and toxicity of chemotherapeutic agents that rely on pyrimidine metabolism. Dihydrouracil is widely used in studies focusing on cancer treatment response and personalized medicine applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 504-07-4 |
| Applications | Metabolite of Uracil |
| Formula | C4H6N2O2 |
| Molecular Weight | 114.10 |
| Synonyms | 5,6-Dihydrouracil |
| SMILES | O=C1CCNC(N1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.