Fig. 1 · Structure
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DIM-C-pPhtBu
ER Stress Activator
DIM-C-pPhtBu is an orally active endoplasmic reticulum (ER) stress activator targeting cellular stress pathways. It induces mitochondrial and lysosomal dysfunction, promotes excessive mitosis, increases reactive oxygen species (ROS) production, and triggers an unfolded protein response-mediated cell death in neck cancer cells. This compound exhibits notable antitumor activity, making it a valuable tool for research focused on cancer biology and treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 94944-80-6 |
| Applications | ER Stress Activator |
| Formula | C27H26N2 |
| Molecular Weight | 378.51 |
| SMILES | CC(C)(C)C(C=C1)=CC=C1C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.