Fig. 1 · Structure
Documents & Downloads
Dimethyl 2-oxoglutarate
2-oxoglutarate Derivative
Dimethyl 2-oxoglutarate is a cell-permeable derivative of 2-oxoglutarate, acting primarily as an antioxidant and a modulator of autophagy. This compound has demonstrated efficacy in preventing mitochondrial damage and reducing reactive oxygen species (ROS) production. Additionally, it has been shown to mitigate carbon tetrachloride-induced liver fibrosis. Dimethyl 2-oxoglutarate is applicable in research focused on various conditions, including Alzheimer's disease, diabetes, and cardiomyopathy.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 13192-04-6 |
| Applications | 2-oxoglutarate Derivative |
| Formula | C7H10O5 |
| Molecular Weight | 174.15 |
| Synonyms | Dimethyl α-ketoglutarate |
| SMILES | O=C(OC)C(CCC(OC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.