Fig. 1 · Structure
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Dimethyl fumarate-d2
Stable Isotope
Dimethyl fumarate-d2 is a deuterated form of Dimethyl fumarate, a recognized Nrf2 activator that enhances antioxidant gene expression via oral administration and effective brain penetration. This compound is known to induce necroptosis in colon cancer cells through mechanisms involving glutathione (GSH) depletion, reactive oxygen species (ROS) accumulation, and MAPK activation, while also promoting autophagy. Dimethyl fumarate-d2 serves as an important tool for research in multiple sclerosis and cellular stress response studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 23057-98-9 |
| Applications | Stable Isotope |
| Formula | C6H6D2O4 |
| Molecular Weight | 146.14 |
| SMILES | O=C(OC)/C([2H])=C([2H])/C(OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.