Fig. 1 · Structure
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Dimethyl itaconate
ROS Inducer
Dimethyl itaconate acts as a reactive oxygen species (ROS) inducer and is known for its immunomodulatory properties. It enhances innate immune memory (trained immunity) while inhibiting microglial activation, thereby reducing neuroinflammation and synaptic structural damage. Additionally, dimethyl itaconate has been shown to influence the composition of intestinal microbiota, making it useful for studies related to immune response and neuroinflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 617-52-7 |
| Applications | ROS Inducer |
| Formula | C7H10O4 |
| Molecular Weight | 158.15 |
| SMILES | C(C(C(OC)=O)=C)C(OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.