Fig. 1 · Structure
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Dimethyl lithospermate B
Sodium Channel Agonist
Dimethyl lithospermate B is a selective sodium channel agonist that enhances sodium current (INa) by slowing its inactivation. This activity results in an increased inward current during the early phases of the action potential (AP). Dimethyl lithospermate B is utilized in research applications focusing on cardiac and neuronal excitability.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 875313-64-7 |
| Applications | Sodium Channel Agonist |
| Formula | C38H34O16 |
| Molecular Weight | 746.67 |
| Synonyms | dmLSB |
| SMILES | OC1=C(O)C=CC(C[C@H](C(OC)=O)OC([C@H]2C3=C(/C=C/C(O[C@@H](C(OC)=O)CC4=CC(O)=C(O)C=C4)=O)C=CC(O)=C3O[C@@H]2C5=CC(O)=C(O)C=C5)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.