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Dinalbuphine sebacate

Prodrug of Nalbuphine

Dinalbuphine sebacate is a prodrug of Nalbuphine, primarily acting as a κ-opioid receptor agonist and a μ-opioid receptor partial antagonist. Upon hydrolysis, it releases Nalbuphine, offering sustained analgesic effects for up to 7 days. This compound is utilized for the management of moderate to severe postoperative pain, making it a valuable tool in pain management research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	311768-81-7
Applications	Prodrug of Nalbuphine
Formula	C₅₂H₆₈N₂O₁₀
Molecular Weight	881.10
Synonyms	Sebacoyldinalbuphine
SMILES	O[C@]12[C@@]34C5=C(C[C@@]2([H])N(CC6CCC6)CC4)C=CC(OC(CCCCCCCCC(OC7=C8C9=C(C=C7)C[C@](N(CC%10CCC%10)CC%11)([H])[C@@]%12(O)[C@]9%11[C@@]([C@H](CC%12)O)([H])O8)=O)=O)=C5O[C@@]3([H])[C@@H](O)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.