Fig. 1 · Structure
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Dios-Arg diTFA
Cationic Lipid
Dios-Arg diTFA is a cationic lipid characterized by an arginine-derived headgroup that exhibits distinct double bond proton signals around 5.2-5.3 ppm. This compound is employed in the formation of cationic lipid nanoparticles (LNPs) when combined with DOPE, facilitating the effective binding of siRNA and plasmids for enhanced intracellular delivery. Its application is vital in gene delivery research and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1807353-31-6 |
| Applications | Cationic Lipid |
| Formula | C43H67F6N5O9 |
| Molecular Weight | 912.01 |
| SMILES | [H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](OC(CCCCCNC([C@@H](N)CCCNC(N)=N)=O)=O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H].O=C(O)C(F)(F)F.O=C(O)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.