Fig. 1 · Structure

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Diphenhydramine-d6 hydrochloride

Stable Isotope

Diphenhydramine-d6 hydrochloride is a deuterated form of Diphenhydramine hydrochloride, a first-generation histamine H1-receptor antagonist known for its anticholinergic properties. This stable isotope can effectively traverse the blood-brain barrier, making it a valuable tool for neurological studies. It is commonly used in research involving pharmacokinetics and metabolic pathways of histamine H1-receptor antagonists, allowing for enhanced tracing of drug dynamics in biological systems.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1189986-72-8
Applications Stable Isotope
Formula C17H16D6ClNO
Molecular Weight 297.85
SMILES
[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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