Fig. 1 · Structure
Documents & Downloads
Diphenylcyclopropenone
Hapten/Immunomodulatory Agent
Diphenylcyclopropenone is a hapten that functions as a topical immunomodulatory agent, effectively inducing allergic contact dermatitis. It promotes an increase in cell-surface thiols in THP-1 human monocytic cells and acts on autoreactive T-lymphocytes, triggering apoptosis within the follicular environment. This compound is relevant for research applications in alopecia areata and related immunological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 886-38-4 |
| Applications | Hapten/Immunomodulatory Agent |
| Formula | C15H10O |
| Molecular Weight | 206.24 |
| Synonyms | Diphencyprone |
| SMILES | O=C1C(C2=CC=CC=C2)=C1C3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.