Fig. 1 · Structure
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Direct Blue 1
VGLUT Inhibitor
Direct Blue 1 is a potent and competitive inhibitor of the vesicular glutamate transporter (VGLUT). This complex dye is primarily utilized in immunofluorescence histochemistry to reduce background autofluorescence. Additionally, Direct Blue 1 exhibits the ability to inhibit Aβ-binding small molecule PrP ligands and demonstrates anti-inflammatory activity, making it valuable in research applications focused on neurodegenerative diseases and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2610-05-1 |
| Applications | VGLUT Inhibitor |
| Formula | C34H24N6Na4O16S4 |
| Molecular Weight | 992.80 |
| Synonyms | Chicago Sky Blue 6B |
| SMILES | COC1=CC(C2=CC=C(/N=N/C3=C(O)C4=C(N)C(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C4C=C3)C(OC)=C2)=CC=C1/N=N/C5=C(O)C6=C(N)C(S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C6C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.