Fig. 1 · Structure
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Ditercalinium chloride
Anticancer Agent
Ditercalinium chloride is an anticancer agent that primarily inhibits human DNA polymerase gamma activity, leading to the depletion of mitochondrial DNA in both mouse and human cells. This compound also shows potential as a ligand against the COMMD10-AP3S1 fusion protein, making it a valuable tool for investigating mitochondrial function and cancer biology. Ditercalinium chloride is suitable for research applications focusing on cancer therapeutics and mitochondrial dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 74517-42-3 |
| Applications | Anticancer Agent |
| Formula | C46H50Cl2N6O2 |
| Molecular Weight | 789.83 |
| Synonyms | NSC335153 |
| SMILES | COC1=CC2=C(NC3=C2C4=C[N+](CCN5CCC(C6CCN(CC[N+]7=CC=C8C=CC(NC9=C%10C=C(OC)C=C9)=C%10C8=C7)CC6)CC5)=CC=C4C=C3)C=C1.[Cl-].[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.