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DIZ-3

Multimeric G4 Ligand

DIZ-3 is a selective multimeric G4 ligand that stabilizes G-quadruplex (G4) structures by intercalating at the G4-G4 interface. This compound effectively induces cell cycle arrest and apoptosis, thereby inhibiting cell proliferation in alternative lengthening of telomere (ALT) cancer cells. DIZ-3 serves as a valuable tool for researchers investigating G4-targeted therapies and the underlying mechanisms of telomere maintenance in cancer.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2675490-72-7
Applications	Multimeric G4 Ligand
Formula	C₄₆H₄₄F₂N₈
Molecular Weight	746.89
SMILES	CN1CCN(CC1)C2=CC=C(C=C2)C3=C(NC(C4=CC=C(C=C4)C5=NC(C6=CC=C(C=C6)F)=C(N5)C7=CC=C(C=C7)N8CCN(CC8)C)=N3)C9=CC=C(C=C9)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.