Fig. 1 · Structure
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DJ001
PTPσ Inhibitor
DJ001 is a selective non-competitive inhibitor of protein tyrosine phosphatase-σ (PTPσ), exhibiting an IC50 of 1.43 μM. This compound demonstrates specificity for PTPσ, showing minimal inhibitory effects on other phosphatases, including only modest activity against Protein Phosphatase 5. DJ001 is valuable for research applications focusing on hematopoietic stem cell regeneration and related signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2161305-12-8 |
| Applications | PTPσ Inhibitor |
| Formula | C15H12N2O3 |
| Molecular Weight | 268.27 |
| SMILES | O=C(C1=CC=CC=C1)/C=C\NC2=CC=CC([N+]([O-])=O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.