Fig. 1 · Structure
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DL-Acetylshikonin
Cytochrome P450 Inhibitor
DL-Acetylshikonin is a reversible, non-selective inhibitor of cytochrome P450 enzymes, demonstrating IC50 values between 1.4 and 4.0 μM. This compound exhibits notable anti-cancer and anti-inflammatory activities, making it a valuable tool in cancer research and studies focused on inflammation pathways. Its inhibition of cytochrome P450 provides insights into drug metabolism and therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 54984-93-9 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C18H18O6 |
| Molecular Weight | 330.33 |
| SMILES | C/C(C)=C\CC(OC(C)=O)C1=CC(C2=C(O)C=CC(O)=C2C1=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.