Fig. 1 · Structure
Documents & Downloads
DL-AP4 sodium
mGluR Agonist
DL-AP4 sodium (2-Amino-4-phosphonobutyric acid sodium) is a potent agonist for metabotropic glutamate receptors (mGluR), specifically targeting mGluR4. This compound activates a signaling pathway that inhibits adenylate cyclase activity, consequently reducing Forskolin-induced cAMP production. Additionally, DL-AP4 sodium functions as an inhibitor of ON channels, leading to decreased sensitivity of photoreceptors to variations in brightness. These properties make it a valuable tool for research in neuropharmacology and synaptic plasticity.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1263093-79-3 |
| Applications | mGluR Agonist |
| Formula | C4H9NNaO5P |
| Molecular Weight | 205.08 |
| Synonyms | 2-Amino-4-phosphonobutyric acid sodium |
| SMILES | OC(C(N)CCP(O)(O[Na])=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.