DLK-IN-1

Catalog No.: A18676

DLK,/MAP3K12 inhibitor

DLK-IN-1

DLK-IN-1 Chemical Structure

CAS NO. 1620574-24-4

DLK-IN-1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM.

Availability: In stock

Package Price Qty
5 mg
$450.00
10 mg
$775.00
50 mg
$2,300.00
100 mg
$4,600.00
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Biological Activity

DLK-IN-1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.62 mL 118.08 mL 236.17 mL
0.5 mM 4.72 mL 23.62 mL 47.23 mL
1 mM 2.36 mL 11.81 mL 23.62 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 423.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18676
Actions Inhibitor
CAS No. 1620574-24-4
Formula C20H24F3N5O2
M. Wt 423.43
Purity >98%
SMILES CC(N1C([[email protected]@H]2[[email protected]]3([H])[[email protected]@]2([H])CN(C4COC4)C3)=CC(C5=CN=C(N)C(OC(F)(F)F)=C5)=N1)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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