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DLK-IN-2

DLK Inhibitor

DLK-IN-2 is a selective inhibitor of dual leucine zipper kinase (DLK), demonstrating neuroprotective properties. It effectively inhibits acute axonal palmitoylation of DLK, blocks DLK-dependent pro-degenerative axon-to-soma retrograde signaling, and suppresses c-Jun phosphorylation. This compound is suitable for research applications focused on the mechanisms underlying neurodegenerative diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	883012-32-6
Applications	DLK Inhibitor
Formula	C₂₃H₂₅ClN₂O₃S
Molecular Weight	444.97
SMILES	O=S(C1=CC=C(NC(C2=CC=C(Cl)C=C2)=O)C=C1)(NC34CC5CC(C4)CC(C5)C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.