DM1-SMCC

Catalog No.: A15955

potent EGFR inhibitor

DM1-SMCC

DM1-SMCC Chemical Structure

CAS NO. 1228105-51-8

DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $180.00

Special Price $144.00

5 mg

Regular Price: $270.00

Special Price $216.00

10 mg

Regular Price: $465.00

Special Price $372.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.32 mL 46.61 mL 93.23 mL
0.5 mM 1.86 mL 9.32 mL 18.65 mL
1 mM 0.93 mL 4.66 mL 9.32 mL
5 mM 0.19 mL 0.93 mL 1.86 mL

*The above data is based on the productmolecular weight 1072.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15955
Actions Inhibitor
CAS No. 1228105-51-8
Formula C51H66ClN5O16S
M. Wt 1072.62
Purity >98%
Synonyms DM1 SMCC, DM1SMCC
SMILES C[[email protected]@H]1[[email protected]@H]2C[[email protected]](NC(O2)=O)(O)[[email protected]](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[[email protected]@H](OC([[email protected]@H](N(C(CCSC(C(N4CC5CCC(C(ON6C(CCC6=O)=O)=O)CC5)=O)CC4=O)=O)C)C)=O)[[email protected]@]7(C)C1O7)=O)=C(Cl)C(OC)=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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