Fig. 1 · Structure
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DMAB-anabaseine dihydrochloride
α7-AChR Agonist/α4β2 nAChR Antagonist
DMAB-anabaseine dihydrochloride acts as a selective partial agonist at the α7 nicotinic acetylcholine receptor (nAChR) and an antagonist at the α4β2 nAChR. This compound has been shown to enhance cognitive function, making it a valuable tool for research in neuropharmacology and cognitive disorders. Its unique receptor profile highlights its potential applications in investigating therapeutic strategies for enhancing cognition and treating related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 154149-38-9 |
| Applications | α7-AChR Agonist/α4β2 nAChR Antagonist |
| Formula | C19H23Cl2N3 |
| Molecular Weight | 364.31 |
| SMILES | CN(C)C(C=C1)=CC=C1/C=C2C(C3=CN=CC=C3)=NCCC/2.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.